Description of ExAtlas
ExAtlas is a tool for meta-analysis of gene expression data. In contrast to other
software, it compares multi-component data sets and generates results for all
combinations (e.g., all gene expression profiles vs. all GO annotations). Main functions are:
(1) standard meta-analysis (fixed and random effects, z-score, Fisher's method; analysis of
(2) global correlations between gene expression data sets;
(3) gene set enrichment;
(4) gene set overlap;
(5) gene association (Expected Proportion of False Positives, EPFP);
(6) statistical analysis of gene expression (ANOVA, PCA, FDR).
Results are presented graphically as heatmaps, bar-charts, or 3-D images (PCA).
Gene expression data is extracted automatically from GEO/NCBI database. Several most popular
public data sets (e.g., GNF, Gene Ontology, KEGG, GAD phenotypes)
are pre-loaded and can be used for functional annotations.
HELP: A guide to ExAtlas.
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How to cite ExAtlas: Sharov, A.A., Schlessinger, D., and Ko, M.S.H. 2015. Exatlas: An
interactive online tool for meta-analysis of gene expression data.
J. Bioinform. Comput. Biol., DOI: 10.1142/S0219720015500195.
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