NIA Mouse Gene Index, mm9

1660. U076257
Annotation: amyotrophic lateral sclerosis 2 (juvenile) homolog (human)     Gene?: Yes     Source: NM_028717    Symbol:  Als2 Mpp4
Chromosome: chr1   Strand: -    Start: 59177778    End: 59294075
List: Negative strand of chr1 (N=6229)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR004172 - L27
IPR014775 - L27, C-terminal
IPR008144 - Guanylate kinase
IPR003123 - Vacuolar sorting protein 9
IPR001452 - Src homology-3
IPR011511 - Variant SH3
IPR001478 - PDZ/DHR/GLGF
IPR001849 - Pleckstrin-like
IPR008145 - Guanylate kinase/L-type calcium channel region
IPR000219 - DH
IPR003409 - MORN motif
IPR013995 - Vacuolar sorting protein 9, subgroup

GO-Ontologies
GO:0032313 - regulation of Rab GTPase activity
GO:0043234 - protein complex
GO:0030676 - Rac guanyl-nucleotide exchange factor activity
GO:0035249 - synaptic transmission, glutamatergic
GO:0005813 - centrosome
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0007041 - lysosomal transport
GO:0005737 - cytoplasm
GO:0005515 - protein binding
GO:0043197 - dendritic spine
GO:0048365 - Rac GTPase binding
GO:0035023 - regulation of Rho protein signal transduction
GO:0051260 - protein homooligomerization
GO:0008104 - protein localization
GO:0005575 - cellular_component
GO:0016197 - endosome transport
GO:0043025 - neuronal cell body
GO:0042802 - identical protein binding
GO:0014069 - postsynaptic density
GO:0016020 - membrane
GO:0016601 - Rac protein signal transduction
GO:0005769 - early endosome
GO:0071902 - positive regulation of protein serine/threonine kinase activity
GO:0016050 - vesicle organization
GO:0045860 - positive regulation of protein kinase activity
GO:0007032 - endosome organization
GO:0007626 - locomotory behavior
GO:0008150 - biological_process
GO:0001881 - receptor recycling
GO:0017112 - Rab guanyl-nucleotide exchange factor activity
GO:0005622 - intracellular
GO:0030426 - growth cone
GO:0017137 - Rab GTPase binding
GO:0030027 - lamellipodium
GO:0030425 - dendrite
GO:0008219 - cell death
GO:0007528 - neuromuscular junction development
GO:0030675 - Rac GTPase activator activity
GO:0042598 - vesicular fraction
GO:0032855 - positive regulation of Rac GTPase activity
GO:0001662 - behavioral fear response
GO:0005792 - microsome
GO:0042803 - protein homodimerization activity
GO:0030424 - axon
GO:0005102 - receptor binding
GO:0005089 - Rho guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005097 - Rab GTPase activator activity
GO:0048812 - neuron projection morphogenesis
GO:0001726 - ruffle
GO:0007409 - axonogenesis
GO:0006979 - response to oxidative stress
GO:0019717 - synaptosome
GO:0043539 - protein serine/threonine kinase activator activity