NIA Mouse Gene Index, mm9

2081. U015575
Annotation: apurinic/apyrimidinic endonuclease 1     Gene?: Yes     Source: NM_009687    Symbol:  Apex1
Chromosome: chr14   Strand: +    Start: 51544623    End: 51546863
List: Positive strand of chr14 (N=4428)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR000300 - Inositol polyphosphate related phosphatase
IPR005135 - Endonuclease/exonuclease/phosphatase

GO-Ontologies
GO:0016607 - nuclear speck
GO:0070301 - cellular response to hydrogen peroxide
GO:0080111 - DNA demethylation
GO:0006974 - response to DNA damage stimulus
GO:0003906 - DNA-(apurinic or apyrimidinic site) lyase activity
GO:0005813 - centrosome
GO:0003677 - DNA binding
GO:0005737 - cytoplasm
GO:0016491 - oxidoreductase activity
GO:0005667 - transcription factor complex
GO:0006310 - DNA recombination
GO:0005730 - nucleolus
GO:0014912 - negative regulation of smooth muscle cell migration
GO:0005654 - nucleoplasm
GO:0045454 - cell redox homeostasis
GO:0007568 - aging
GO:0006351 - transcription, DNA-dependent
GO:0051059 - NF-kappaB binding
GO:0045768 - positive regulation of anti-apoptosis
GO:0003684 - damaged DNA binding
GO:0032403 - protein complex binding
GO:0006355 - regulation of transcription, DNA-dependent
GO:0008408 - 3'-5' exonuclease activity
GO:0016829 - lyase activity
GO:0003713 - transcription coactivator activity
GO:0045750 - positive regulation of S phase of mitotic cell cycle
GO:0016787 - hydrolase activity
GO:0043488 - regulation of mRNA stability
GO:0005622 - intracellular
GO:0004518 - nuclease activity
GO:0055114 - oxidation-reduction process
GO:0004527 - exonuclease activity
GO:0046872 - metal ion binding
GO:0004519 - endonuclease activity
GO:0003723 - RNA binding
GO:0031490 - chromatin DNA binding
GO:0048471 - perinuclear region of cytoplasm
GO:0016890 - site-specific endodeoxyribonuclease activity, specific for altered base
GO:0004521 - endoribonuclease activity
GO:0005783 - endoplasmic reticulum
GO:0005739 - mitochondrion
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0045739 - positive regulation of DNA repair