NIA Mouse Gene Index, mm9

2588. U025252
Annotation: cyclin-dependent kinase inhibitor 2A     Gene?: Yes     Source: NM_009877    Symbol:  Cdkn2a
Chromosome: chr4   Strand: -    Start: 88920376    End: 88940557
List: Negative strand of chr4 (N=5845)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR010868 - Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal
IPR002110 - Ankyrin

GO-Ontologies
GO:0051091 - positive regulation of sequence-specific DNA binding transcription factor activity
GO:0035985 - senescence-associated heterochromatin focus
GO:0008134 - transcription factor binding
GO:0031648 - protein destabilization
GO:0071158 - positive regulation of cell cycle arrest
GO:2000774 - positive regulation of cellular senescence
GO:0003677 - DNA binding
GO:0006469 - negative regulation of protein kinase activity
GO:0035986 - senescence-associated heterochromatin focus formation
GO:0005515 - protein binding
GO:0010389 - regulation of G2/M transition of mitotic cell cycle
GO:0006915 - apoptotic process
GO:0006919 - activation of caspase activity
GO:0005730 - nucleolus
GO:0009303 - rRNA transcription
GO:0007569 - cell aging
GO:0005654 - nucleoplasm
GO:0045892 - negative regulation of transcription, DNA-dependent
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0000079 - regulation of cyclin-dependent protein kinase activity
GO:0007568 - aging
GO:0060058 - positive regulation of apoptosis involved in mammary gland involution
GO:0006309 - DNA fragmentation involved in apoptotic nuclear change
GO:0006355 - regulation of transcription, DNA-dependent
GO:0031647 - regulation of protein stability
GO:0003700 - sequence-specific DNA binding transcription factor activity
GO:0048103 - somatic stem cell division
GO:0010243 - response to organic nitrogen
GO:0030308 - negative regulation of cell growth
GO:0006364 - rRNA processing
GO:0008637 - apoptotic mitochondrial changes
GO:0033600 - negative regulation of mammary gland epithelial cell proliferation
GO:0043517 - positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0030889 - negative regulation of B cell proliferation
GO:0000075 - cell cycle checkpoint
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0006917 - induction of apoptosis
GO:0033088 - negative regulation of immature T cell proliferation in thymus
GO:2000111 - positive regulation of macrophage apoptosis
GO:0070215 - MDM2 binding
GO:0008544 - epidermis development
GO:0043234 - protein complex
GO:0042326 - negative regulation of phosphorylation
GO:0005737 - cytoplasm
GO:0090399 - replicative senescence
GO:0070534 - protein K63-linked ubiquitination
GO:0007050 - cell cycle arrest
GO:0055105 - ubiquitin-protein ligase inhibitor activity
GO:0006351 - transcription, DNA-dependent
GO:0051059 - NF-kappaB binding
GO:0046822 - regulation of nucleocytoplasmic transport
GO:0001953 - negative regulation of cell-matrix adhesion
GO:0007049 - cell cycle
GO:0033235 - positive regulation of protein sumoylation
GO:0034393 - positive regulation of smooth muscle cell apoptosis
GO:0051444 - negative regulation of ubiquitin-protein ligase activity
GO:0000209 - protein polyubiquitination
GO:0035019 - somatic stem cell maintenance
GO:0090398 - cellular senescence
GO:0014070 - response to organic cyclic compound
GO:0002039 - p53 binding
GO:0046825 - regulation of protein export from nucleus
GO:0004861 - cyclin-dependent protein kinase inhibitor activity
GO:0042493 - response to drug
GO:0008285 - negative regulation of cell proliferation
GO:0019901 - protein kinase binding
GO:0005634 - nucleus
GO:0001652 - granular component
GO:0045736 - negative regulation of cyclin-dependent protein kinase activity
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0050821 - protein stabilization
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0010468 - regulation of gene expression
GO:0045786 - negative regulation of cell cycle