NIA Mouse Gene Index, mm9

2477. U008198
Annotation: insulin-like growth factor I receptor     Gene?: Yes     Source: NM_010513    Symbol:  Igf1r
Chromosome: chr7   Strand: +    Start: 75096960    End: 75373603
List: Positive strand of chr7 (N=5672)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR002290 - Serine/threonine protein kinase
IPR003961 - Fibronectin, type III
IPR000494 - EGF receptor, L domain
IPR006212 - Furin-like repeat
IPR006211 - Furin-like cysteine rich region
IPR011019 - KIND
IPR000719 - Protein kinase, core
IPR001245 - Tyrosine protein kinase

GO-Ontologies
GO:0030879 - mammary gland development
GO:0030238 - male sex determination
GO:0005520 - insulin-like growth factor binding
GO:0030010 - establishment of cell polarity
GO:0004672 - protein kinase activity
GO:0005010 - insulin-like growth factor-activated receptor activity
GO:0043548 - phosphatidylinositol 3-kinase binding
GO:0051054 - positive regulation of DNA metabolic process
GO:0005515 - protein binding
GO:0005524 - ATP binding
GO:0000166 - nucleotide binding
GO:0016301 - kinase activity
GO:0043559 - insulin binding
GO:0030335 - positive regulation of cell migration
GO:0051262 - protein tetramerization
GO:0042802 - identical protein binding
GO:0031994 - insulin-like growth factor I binding
GO:0006955 - immune response
GO:0016021 - integral to membrane
GO:0031017 - exocrine pancreas development
GO:0045740 - positive regulation of DNA replication
GO:0048015 - phosphatidylinositol-mediated signaling
GO:0016020 - membrane
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0045768 - positive regulation of anti-apoptosis
GO:0016740 - transferase activity
GO:0005158 - insulin receptor binding
GO:0046777 - protein autophosphorylation
GO:0051291 - protein heterooligomerization
GO:0051897 - positive regulation of protein kinase B signaling cascade
GO:0006468 - protein phosphorylation
GO:0051898 - negative regulation of protein kinase B signaling cascade
GO:0007420 - brain development
GO:0090031 - positive regulation of steroid hormone biosynthetic process
GO:0001965 - G-protein alpha-subunit binding
GO:0009887 - organ morphogenesis
GO:0043005 - neuron projection
GO:0046872 - metal ion binding
GO:0060740 - prostate gland epithelium morphogenesis
GO:0016310 - phosphorylation
GO:0043560 - insulin receptor substrate binding
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0031175 - neuron projection development
GO:0048009 - insulin-like growth factor receptor signaling pathway
GO:0005901 - caveola
GO:0004713 - protein tyrosine kinase activity
GO:0005792 - microsome
GO:0005886 - plasma membrane
GO:0007169 - transmembrane receptor protein tyrosine kinase signaling pathway
GO:0032467 - positive regulation of cytokinesis
GO:0043409 - negative regulation of MAPKKK cascade
GO:0043410 - positive regulation of MAPKKK cascade
GO:0007409 - axonogenesis
GO:0004872 - receptor activity