NIA Mouse Gene Index, mm9

5140. U023344
Annotation: interleukin 1 beta     Gene?: Yes     Source: NM_008361    Symbol:  Il1b
Chromosome: chr2   Strand: -    Start: 129190305    End: 129196875
List: Negative strand of chr2 (N=7531)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR000975 - Interleukin-1
IPR003502 - Interleukin-1 propeptide

GO-Ontologies
GO:0030593 - neutrophil chemotaxis
GO:0051091 - positive regulation of sequence-specific DNA binding transcription factor activity
GO:0030141 - secretory granule
GO:0033198 - response to ATP
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
GO:0019904 - protein domain specific binding
GO:0032496 - response to lipopolysaccharide
GO:0070164 - negative regulation of adiponectin secretion
GO:0001660 - fever generation
GO:0005576 - extracellular region
GO:0006955 - immune response
GO:0005615 - extracellular space
GO:0050995 - negative regulation of lipid catabolic process
GO:0007568 - aging
GO:0010575 - positive regulation vascular endothelial growth factor production
GO:0042221 - response to chemical stimulus
GO:0000187 - activation of MAPK activity
GO:0032757 - positive regulation of interleukin-8 production
GO:0032729 - positive regulation of interferon-gamma production
GO:0050796 - regulation of insulin secretion
GO:0042346 - positive regulation of NF-kappaB import into nucleus
GO:0045410 - positive regulation of interleukin-6 biosynthetic process
GO:0007613 - memory
GO:0032308 - positive regulation of prostaglandin secretion
GO:0043123 - positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050996 - positive regulation of lipid catabolic process
GO:0032874 - positive regulation of stress-activated MAPK cascade
GO:0010829 - negative regulation of glucose transport
GO:0071310 - cellular response to organic substance
GO:0043122 - regulation of I-kappaB kinase/NF-kappaB cascade
GO:0007204 - elevation of cytosolic calcium ion concentration
GO:0045080 - positive regulation of chemokine biosynthetic process
GO:0001934 - positive regulation of protein phosphorylation
GO:0071639 - positive regulation of monocyte chemotactic protein-1 production
GO:0019221 - cytokine-mediated signaling pathway
GO:0042102 - positive regulation of T cell proliferation
GO:0051781 - positive regulation of cell division
GO:0045429 - positive regulation of nitric oxide biosynthetic process
GO:0045833 - negative regulation of lipid metabolic process
GO:0005125 - cytokine activity
GO:0035505 - positive regulation of myosin light chain kinase activity
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
GO:0035690 - cellular response to drug
GO:0031982 - vesicle
GO:0060559 - positive regulation of calcidiol 1-monooxygenase activity
GO:0043407 - negative regulation of MAP kinase activity
GO:0043507 - positive regulation of JUN kinase activity
GO:0008083 - growth factor activity
GO:0032611 - interleukin-1 beta production
GO:0046330 - positive regulation of JNK cascade
GO:0006954 - inflammatory response
GO:0006916 - anti-apoptosis
GO:0010628 - positive regulation of gene expression
GO:0035176 - social behavior
GO:0045086 - positive regulation of interleukin-2 biosynthetic process
GO:0045766 - positive regulation of angiogenesis
GO:0032755 - positive regulation of interleukin-6 production
GO:0005149 - interleukin-1 receptor binding
GO:0032725 - positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0046627 - negative regulation of insulin receptor signaling pathway
GO:0031622 - positive regulation of fever generation
GO:0045840 - positive regulation of mitosis
GO:0014050 - negative regulation of glutamate secretion
GO:0008285 - negative regulation of cell proliferation
GO:0030730 - sequestering of triglyceride
GO:0050900 - leukocyte migration
GO:0043065 - positive regulation of apoptotic process
GO:0051044 - positive regulation of membrane protein ectodomain proteolysis
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter