NIA Mouse Gene Index, mm9

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4360. U008656

Annotation: phosphodiesterase 3B, cGMP-inhibited     Gene?: Yes     Source: NM_011055    Symbol:  Pde3b
Chromosome: chr7   Strand: +    Start: 121558674    End: 121682765
List: Positive strand of chr7 (N=5672)

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Genome Browsers: UCSC -

View Regulatory Regions

Exon structure

Domains

IPR003607 - Metal-dependent phosphohydrolase, HD region

IPR002038 - Osteopontin

IPR009495 - Protein of unknown function DUF1109

IPR007895 - MASE1

IPR007015 - DNA polymerase V

IPR002073 - 3'5'-cyclic nucleotide phosphodiesterase

IPR004695 - C4-dicarboxylate transporter/malic acid transport protein

GO-Ontologies

GO:0007165 - signal transduction

GO:0016787 - hydrolase activity

GO:0030552 - cAMP binding

GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity

GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity

GO:0008081 - phosphoric diester hydrolase activity

GO:0046872 - metal ion binding

GO:0051219 - phosphoprotein binding

GO:0005626 - insoluble fraction

GO:0005794 - Golgi apparatus

GO:0046676 - negative regulation of insulin secretion

GO:0008144 - drug binding

GO:0004119 - cGMP-inhibited cyclic-nucleotide phosphodiesterase activity

GO:0016021 - integral to membrane

GO:0005792 - microsome

GO:0043422 - protein kinase B binding

GO:0050995 - negative regulation of lipid catabolic process

GO:0006198 - cAMP catabolic process

GO:0016020 - membrane

GO:0032045 - guanyl-nucleotide exchange factor complex

GO:0005783 - endoplasmic reticulum

GO:0003824 - catalytic activity

GO:0031018 - endocrine pancreas development

GO:0007162 - negative regulation of cell adhesion

GO:0042593 - glucose homeostasis

GO:0050796 - regulation of insulin secretion