NIA Mouse Gene Index, mm9

4617. U008728
Annotation: polo-like kinase 1 (Drosophila)     Gene?: Yes     Source: NM_011121    Symbol:  Plk1
Chromosome: chr7   Strand: +    Start: 129302948    End: 129313192
List: Positive strand of chr7 (N=5672)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR002290 - Serine/threonine protein kinase
IPR011019 - KIND
IPR000719 - Protein kinase, core
IPR000959 - POLO box duplicated region
IPR001245 - Tyrosine protein kinase

GO-Ontologies
GO:0031648 - protein destabilization
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0005813 - centrosome
GO:0004672 - protein kinase activity
GO:0005737 - cytoplasm
GO:0043393 - regulation of protein binding
GO:0031572 - G2/M transition DNA damage checkpoint
GO:0005524 - ATP binding
GO:0000166 - nucleotide binding
GO:0018105 - peptidyl-serine phosphorylation
GO:0016301 - kinase activity
GO:0000775 - chromosome, centromeric region
GO:0051233 - spindle midzone
GO:0000236 - mitotic prometaphase
GO:0010800 - positive regulation of peptidyl-threonine phosphorylation
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0016740 - transferase activity
GO:0000776 - kinetochore
GO:0040038 - polar body extrusion after meiotic divisions
GO:0007346 - regulation of mitotic cell cycle
GO:0007049 - cell cycle
GO:0010997 - anaphase-promoting complex binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005694 - chromosome
GO:0000942 - condensed nuclear chromosome outer kinetochore
GO:0006468 - protein phosphorylation
GO:0071168 - protein localization to chromatin
GO:0051443 - positive regulation of ubiquitin-protein ligase activity
GO:0016567 - protein ubiquitination
GO:0090007 - regulation of mitotic anaphase
GO:0016310 - phosphorylation
GO:0005856 - cytoskeleton
GO:0051301 - cell division
GO:0007067 - mitosis
GO:0030496 - midbody
GO:0005634 - nucleus
GO:0000922 - spindle pole
GO:0019901 - protein kinase binding
GO:0045736 - negative regulation of cyclin-dependent protein kinase activity
GO:0005876 - spindle microtubule
GO:0045862 - positive regulation of proteolysis