NIA Mouse Gene Index, mm9

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1734. U014851

Annotation: spleen tyrosine kinase     Gene?: Yes     Source: NM_001198977    Symbol:  Sykb
Chromosome: chr13   Strand: +    Start: 52678288    End: 52744161
List: Positive strand of chr13 (N=4247)

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Genome Browsers: UCSC -

View Regulatory Regions

Exon structure

Domains

IPR002290 - Serine/threonine protein kinase

IPR011019 - KIND

IPR000719 - Protein kinase, core

IPR001245 - Tyrosine protein kinase

IPR000980 - SH2 motif

GO-Ontologies

GO:0043306 - positive regulation of mast cell degranulation

GO:0030593 - neutrophil chemotaxis

GO:0004672 - protein kinase activity

GO:0019904 - protein domain specific binding

GO:0005737 - cytoplasm

GO:0005524 - ATP binding

GO:0004716 - receptor signaling protein tyrosine kinase activity

GO:0005515 - protein binding

GO:0000166 - nucleotide binding

GO:0016301 - kinase activity

GO:0007159 - leukocyte cell-cell adhesion

GO:0045588 - positive regulation of gamma-delta T cell differentiation

GO:0007167 - enzyme linked receptor protein signaling pathway

GO:0045425 - positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process

GO:0016772 - transferase activity, transferring phosphorus-containing groups

GO:0000187 - activation of MAPK activity

GO:0016740 - transferase activity

GO:0043366 - beta selection

GO:0046777 - protein autophosphorylation

GO:0019370 - leukotriene biosynthetic process

GO:0045579 - positive regulation of B cell differentiation

GO:0042101 - T cell receptor complex

GO:0046638 - positive regulation of alpha-beta T cell differentiation

GO:0050776 - regulation of immune response

GO:0007166 - cell surface receptor linked signaling pathway

GO:0006468 - protein phosphorylation

GO:0007186 - G-protein coupled receptor signaling pathway

GO:0019815 - B cell receptor complex

GO:0018108 - peptidyl-tyrosine phosphorylation

GO:0045401 - positive regulation of interleukin-3 biosynthetic process

GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation

GO:0050853 - B cell receptor signaling pathway

GO:0046641 - positive regulation of alpha-beta T cell proliferation

GO:0016310 - phosphorylation

GO:0001820 - serotonin secretion

GO:0005178 - integrin binding

GO:0004715 - non-membrane spanning protein tyrosine kinase activity

GO:0004713 - protein tyrosine kinase activity

GO:0007257 - activation of JUN kinase activity

GO:0035556 - intracellular signal transduction

GO:0050850 - positive regulation of calcium-mediated signaling

GO:0019901 - protein kinase binding