NIA Mouse Gene Index, mm9

---

1740. U017847

Annotation: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)     Gene?: Yes     Source: NM_013683    Symbol:  Tap1
Chromosome: chr17   Strand: +    Start: 34324497    End: 34334170
List: Positive strand of chr17 (N=4009)

---

Genome Browsers: UCSC -

View Regulatory Regions

Exon structure

Domains

IPR003395 - SMC protein, N-terminal

IPR003593 - AAA+ ATPase, core

IPR001140 - ABC transporter, transmembrane region

IPR003439 - ABC transporter related

GO-Ontologies

GO:0001916 - positive regulation of T cell mediated cytotoxicity

GO:0017111 - nucleoside-triphosphatase activity

GO:0030176 - integral to endoplasmic reticulum membrane

GO:0042626 - ATPase activity, coupled to transmembrane movement of substances

GO:0046978 - TAP1 binding

GO:0015197 - peptide transporter activity

GO:0046979 - TAP2 binding

GO:0005524 - ATP binding

GO:0015421 - oligopeptide-transporting ATPase activity

GO:0000166 - nucleotide binding

GO:0005215 - transporter activity

GO:0046967 - cytosol to ER transport

GO:0016021 - integral to membrane

GO:0016020 - membrane

GO:0043531 - ADP binding

GO:0016887 - ATPase activity

GO:0019885 - antigen processing and presentation of endogenous peptide antigen via MHC class I

GO:0042270 - protection from natural killer cell mediated cytotoxicity

GO:0055085 - transmembrane transport

GO:0046980 - tapasin binding

GO:0006952 - defense response

GO:0006810 - transport

GO:0042825 - TAP complex

GO:0005792 - microsome

GO:0042803 - protein homodimerization activity

GO:0005783 - endoplasmic reticulum

GO:0042605 - peptide antigen binding

GO:0005886 - plasma membrane

GO:0015031 - protein transport

GO:0005739 - mitochondrion

GO:0008152 - metabolic process

GO:0006200 - ATP catabolic process

GO:0019060 - intracellular transport of viral proteins in host cell

GO:0046982 - protein heterodimerization activity

GO:0015833 - peptide transport

GO:0042288 - MHC class I protein binding