NIA Mouse Gene Index, mm9

890. U037530
Annotation: tuberous sclerosis 2     Gene?: Yes     Source: NM_011647    Symbol:  Tsc2
Chromosome: chr17   Strand: -    Start: 24732760    End: 24769575
List: Negative strand of chr17 (N=3916)

Genome Browsers: UCSC -
View Regulatory Regions


Exon structure

Domains
IPR000331 - Rap/ran-GAP
IPR003913 - Tuberin

GO-Ontologies
GO:0043234 - protein complex
GO:0007165 - signal transduction
GO:0005096 - GTPase activator activity
GO:0007507 - heart development
GO:0005829 - cytosol
GO:0005737 - cytoplasm
GO:0006469 - negative regulation of protein kinase activity
GO:0043547 - positive regulation of GTPase activity
GO:0005515 - protein binding
GO:0014065 - phosphatidylinositol 3-kinase cascade
GO:0005624 - membrane fraction
GO:0005794 - Golgi apparatus
GO:0051260 - protein homooligomerization
GO:0051726 - regulation of cell cycle
GO:0050680 - negative regulation of epithelial cell proliferation
GO:0019902 - phosphatase binding
GO:0008104 - protein localization
GO:0006953 - acute-phase response
GO:0043025 - neuronal cell body
GO:0001666 - response to hypoxia
GO:0045121 - membrane raft
GO:0043407 - negative regulation of MAP kinase activity
GO:0044430 - cytoskeletal part
GO:0014067 - negative regulation of phosphatidylinositol 3-kinase cascade
GO:0071889 - 14-3-3 protein binding
GO:0006606 - protein import into nucleus
GO:0045792 - negative regulation of cell size
GO:0030100 - regulation of endocytosis
GO:0043491 - protein kinase B signaling cascade
GO:0051291 - protein heterooligomerization
GO:0030178 - negative regulation of Wnt receptor signaling pathway
GO:0030426 - growth cone
GO:0045184 - establishment of protein localization
GO:0051898 - negative regulation of protein kinase B signaling cascade
GO:0043005 - neuron projection
GO:0030425 - dendrite
GO:0048471 - perinuclear region of cytoplasm
GO:0048009 - insulin-like growth factor receptor signaling pathway
GO:0032007 - negative regulation of TOR signaling cascade
GO:0042803 - protein homodimerization activity
GO:0005792 - microsome
GO:0005901 - caveola
GO:0030030 - cell projection organization
GO:0033596 - TSC1-TSC2 complex
GO:0001843 - neural tube closure
GO:0008285 - negative regulation of cell proliferation
GO:0005634 - nucleus
GO:0046626 - regulation of insulin receptor signaling pathway
GO:0046982 - protein heterodimerization activity
GO:0050918 - positive chemotaxis